Abstract MicroRNA-34 (miR-34) has been reported to be dysregulated in various human cancers and regarded as a tumor suppressive microRNA because of its synergistic effect with the well-known tumor suppressor p53.Along with the application of MRX34, the first tumor-targeted microRNA drug which based on miR-34a mimics, on phase I clinical trial (NCT0
Telephone cable Abstract Given the lack of standardized guidance for follow-up of patients with neuronal ceroid lipofucsinosis-2 disease in Latin-American countries and the heterogeneity of the region, an expert panel was created with the participation of 11 pediatric neurologists from Colombia, Argentina, Brazil and Chile.The aim of the expert pan
The process of changing the border line of the Akmola province of the Kazak Autonomous Republic (until 1925 - the Kyrgyz Republic) of the Autonomous Republic with the adjacent territory of the Omsk District of the Siberian Territory (until 1925 - the Omsk Province), consisting in the transition of the Cherlak District (Stepanovskaya, Yeast Formulas